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TOKAI presents here a new standard for ophthalmic lenses which ophthalmic lenses are not just a item for vision correction but a item to help the eyes. The EYE CARE DESIGNs. 

There are many different disorders that may occur to the eyes, which is a very complex organ, important to your healthy life. Out of these disorders, “Age-Related Macular Degeneration” is the most common cause of vision loss for the age group of 50+.

The “Lutein” is one of a carotenoid essential to the eyes, Absorbed by eating yellow and green vegetables.

The Macula is the central area of the retina within the eyes, which helps you see clearly. Studies show that the destruction of the “Lutein” existing within the macula can become the cause of this disorder. The destruction is caused by UV rays. Humans unfortunately can not produce this essential sub- stance alone and depend on eating green and yellow vegetable to take in within the body. This is why TOKAI developed the “LUTINA” to lead the EYE CARE DESIGN. The LUTINA will cut out the UV rays, and help protect the essential Lutein within the eyes.

*Images for Reference


Doctor’s report

Prof. Dr. 
Richard H.W. Funk
Medical Faculty Carl-Gustav-Carus Technical University of Dresden

To maintain a healthy life, it is important to reduce the stress of the eyes.

According to recent studies, it was shown that HEV light (High Energy Violet light) can cause oxidative stress within different layers of the retina – especially the photoreceptors and pigment epithelial cells. The group of Funk (2011a) showed in standardized laboratory experiments by cell culture that neuronal retinal cells react after exposure to short wave length light of 411nm with much higher stress and signs of beginning cell death (apoptosis) than after impingement of 470nm light. Furthermore, the Funk (2011b) group demonstrated that after exposure to 411nm light the retina gets distorted.

These events can also happen in the human retina as one of the factors which accelerates the development of Age-related Macular Degeneration (AMD) evidenced by cell culture and animal studies (Wu et al. 2006, Jarett and Boulton 2012). Also a recent in vitro study demonstrated production of radical oxygen species, DNA damage and initiation of cell death in lens epithelial cells, which can lead to the formation of cortical cataract, after imingement of short wavelength light (Xie et al 2014).Thus it is very useful to block HEV light of 400nm – 420nm, because the light can trigger harmful processes in the eye.

Specially Appointed Prof.
Amane Koizumi
National Institutes of Natural Science

Wearing lenses may save the eye’s health just like taking supplements.

Many eye disorders and the aging of the eyes are believed to be the caused by reactive oxygen , more specifically the singlet oxygen and the oxidative stress caused by it.
From studies, this singlet oxygen is known to be accelerat-ingly produced due to the UV-rays and the high energy light waves. The lutein is a substance that restrains the oxidative stress caused by this singlet oxygen. Not only so but, a body waste called the lipofuscin builds up inside the retinal pigment epithelium as the aging of the eyes proceed.
This lipofuscin acts as a sensitizing agent and accelerates the production of singlet oxygen. The lipofuscin has a characteristic to absorb more light as the light as the light waves gets shorter as of the figure. By cutting out the lights around the area, it is possible to effectively restrain the production of the singlet oxygen, thus can reduce the reduction of lutein within the retina. The lutein its self is a pigment that absorbs the UV – Blue wavelength lights, so by reducing the lights near this wave length, it is possible to reduce the destruction of it directly as well. “LUTINA” cuts out of course the UV-rays like as other lenses but in addition it cuts out light waves from 400-420nm.
400-420nm are the wave length that both the lutein and lipofuscin absorbs, thus by cutting theses light waves out, the “LUTINA” can reduce the oxidative stress and also reduce the damage to the lutein. This area of wave length is actually lights that are not so sensitive so cutting these lights will not effect the Saga dean rhythm which is becoming a popular subject, and more over the color on the lenses will be natural. Wearing “LUTINA” can easily be done daily for the eyes health care just like taking supplements.

The amount of macular pigment reduces with aging.

The amount of macular pigment is likely to reduce withaging,
and this graph shows that the amount of macular pigment in people 60 years old and up is smaller than that in people in their twenties and forties. (See the left figure.)

Relationship between age-related macular degeneration and macular pigment

Damage to visual cells or retinal pigment epithelial cells by light-induced oxidative stress is related closely to the onset of age-related macular degeneration. The amount of macular pigment in patients suffering fromage-related macular degeneration is smaller than that in healthy people of the same age (see the bottom right figure). Another finding is that with regard to those suffering fromage-related macular degeneration with either eye, the amount of macular pigment in the other eye not suffering from thedisease is also small. Judging from these facts, the amount of macular pigment is related to age-related macular degeneration, and people with a small amount of macular pigment are probably likely to develop age-related macular degeneration. In other words, it is important for elderly people in particular to keep lutein-containing macular pigment in the eyes.

How can we help protect the macular pigment?

How can we reduce oxidative stress induced by light and help protect the macular pigment? A solution is wearing LUTINA.
LUTINA is provided with the function of cutting off light of 400 to 420 nm efficiently in addition to the functions conventional
generalultraviolet ray cut-off glass lenses have. You can expectfrom
LUTINA the effect of keeping the macular pigment and protecting theeyes from oxidative stress by cutting off such light.

Why is “LUTINA” highly reputed?

Since the macular pigment controls the scattering of light in the retina, people with much macular pigment can clearly distinguish black and white, which is called contrast, (blurriness is reduced) and feel less glare (for example, the light from oncoming vehicles is glaring or the light from a bulb is garish) in the nighttime. LUTINA can prevent the reduction of macular pigment containing lutein and cut off light, or the source of glare, and is, therefore, helpful in seeing things.

Lutina Development Story

Eye care design glasses created with the hint of eating healthy